【問題】50S protein synthesis inhibitors ?推薦回答

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Erythromycin- and Chloramphenicol-Induced Ribosomal ... - NCBI。

Several protein synthesis inhibitors are known to inhibit ribosome assembly. ... chose two inhibitors of the 50S subunit, erythromycin and chloramphenicol, ...: 。

Discovery and Analysis of Natural-Product Compounds Inhibiting ...。

In high-throughput screens, 13 compounds were identified that inhibit protein synthesis with 50% inhibitory concentrations ranging from 0.3 to >80 μM.: tw | tw。

Erythromycin- and Chloramphenicol-Induced ... - ASM Journals。

Several protein synthesis inhibitors are known to inhibit ribosome assembly. ... Macrolide antibiotics inhibit 50S ribosomal subunit assembly in Bacillus ...。

Discovery and Analysis of 4H-Pyridopyrimidines, a Class of ...。

Macromolecular synthesis (MMS) assays with E. coli and S. aureus confirmed that antibacterial activity resulted from specific inhibition of protein ...。

Cell-type-specific drug-inducible protein synthesis inhibition ... - Nature。

2020年1月20日 · This resulted in 50% reduction in de novo translation followed by rapid clearance of iPKR and phosphorylated (p)-eIF2α S51 within hours after ...。

Inhibition of Protein Synthesis by Antibiotics - Sigma-Aldrich。

However, the majority of antibiotics that block bacterial protein synthesis interfere with the processes at the 30S subunit or 50S subunit of the 70S bacterial ...: 。

Incompatibility of chemical protein synthesis inhibitors with accurate ...。

2017年9月29日 · Experiments were conducted in HepG2 cells and primary rat hepatocytes (PRH). IC50 for actinomycin D, cycloheximide, emetine, and puromycin were ...。

Inhibitors of protein synthesis identified by a high throughput ...。

The majority of known protein synthesis inhibitors bind to ribosomes, ... Dual activity measurements were performed by injecting 50 µl of firefly luciferase ...。

Cycloheximide prevents the de novo polypeptide synthesis required ...。

To date, no AOA-specific protein synthesis inhibitor has been identified. ... 155 mL glass Wheaton-type bottles containing 50 mL SCM supplemented with 0.2 ...


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